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Month: July 2018

Uptake of MC1R Testing for Melanoma Risk

Uptake of MC1R Testing for Melanoma Risk

The use of personalized medicine or tailoring medicine based on sequencing and analyzing an individual’s DNA, is drastically changing cancer research and treatment, risk assessment and clinical practices1, and skin cancer is one area being affected by this research.2 Currently, melanoma in U.S. Hispanic populations is on the rise and despite melanoma being more common in Caucasians than Hispanics, a melanoma diagnosis is more likely to be fatal for Hispanics.3

In a study recently published in JAMA Dermatology, several researchers (lead author Dr. Jennifer Hay) including Dr. David Buller from Klein Buendel, examined interest and uptake, as well as demographic and skin cancer risk factor covariates of interest and uptake, of the melanocortin-1 receptor gene (MC1R) saliva test among 499 adult participants recruited from diverse clinics in Albuquerque, New Mexico. Forty-four percent (44%) of participants were non-Hispanic white, 48% were Hispanic, and all were registered clinic patients for longer than six months, were 18-years of age or older, and spoke English or Spanish fluently. A study website log-in was given to participants to give them the option to log on and read three educational modules presenting the rationale and pros and cons of MC1R testing.

Results showed that almost 50% (n=232) of participants logged on to the website and that non-Hispanic whites and those with higher education were more likely to do so. Furthermore, participants with a history of sunburn and with at least one first-degree relative were also more likely to log on to the website. Of those who logged on, almost 90% (n=204) decided to request testing and a little over 80% (n=167) of those who requested testing returned the kit. Non-Hispanic whites and older participants had a higher rate of returning the kit.

Authors cite the large, diverse sample and the behavioral outcomes versus self-reported outcomes as strengths of the study while citing the single location and use of one primary care health system for recruitment as a limitation on generalizability. Lastly, authors conclude by calling for future research in socioeconomic and demographic discrepancies in interest and uptake of genetic testing in order to ensure ease of availability of genetic information seeking in the general population.

References

  1. Orchard C. Genomic medicine in the real world: “hope” and “hype”. Harvard T.H. Chan School of Public Health Web site. Available at: https://www.hsph.harvard.edu/ecpe/genomic-medicine-in-the-real-world-hope-and-hype/. Published June 1, 2015. Accessed June 20, 2018.
  2. Genetics of skin cancer (PDQ) – health professional version: genetic testing. National Cancer Institute Web site. Available at: https://www.cancer.gov/types/skin/hp/skin-genetics-pdq#link/_393_toc. Updated June 14, 2018. Accessed June 20, 2018.
  3. Perez MI. Hispanics get skin cancer, too. Skin Cancer Foundation Web site. Available at: https://www.skincancer.org/prevention/are-you-at-risk/hispanic. Published May 25, 2016. Accessed June 20, 2018.
Online Responsible Alcohol Beverage Server Training for Spanish Language Populations

Online Responsible Alcohol Beverage Server Training for Spanish Language Populations

Data from a Klein Buendel (KB) research project on the formative development of an online responsible alcohol beverage server training program for Spanish language populations the U.S. Southwest was presented in June at the 41st Annual Scientific Meeting of the Research Society on Alcoholism in San Diego, California.

Preventing alcohol-related injury and death is a national priority. Evidence-based interventions to change organizational and community norms, including training to promote responsible alcohol beverage service (RBS), are important public health approaches. However, current RBS training has not been tailored to address Spanish-speaking populations that represent disproportionately high rates of alcohol-related injury and death in the U.S. WayToServe®, an evidence-based RBS intervention, is being redesigned to promote a culturally and linguistically adapted RBS training for Spanish-speaking servers, titled WayToServe Español.

Four focus groups were conducted with Spanish-speaking alcohol servers to identify linguistic and culturally relevant additions to create WayToServe Español. Focus groups were held in El Paso, Texas, on weekdays in spring 2017, between 1:30-3:00 pm. Of the 37 participants, all were either monolingual or bilingual Spanish-speakers and active or recent alcohol sellers/servers. Research team members conducted the groups. The discussions were audiotaped and transcribed verbatim from Spanish to English. Two team members reviewed all transcripts for recurring ideas and comments and then categorized them into main themes.

Preliminary analysis identified four overarching themes: (1) challenges faced by servers, such as setting clear limits for alcohol service for their patrons; (2) support for RBS training; (3) participants’ evaluations of previous training (for example, the low quality of existing Spanish-language RBS training; and (4) their recommendations for Spanish-language RBS training, such as the importance of culturally-respectful training. Participants noted easy access to the web-based RBS training. Overall, the data suggest that WayToServe Español for Spanish-speaking servers is an important step in the creation of culturally- and linguistically-relevant approaches to enhance RBS.

This research project is titled “WayToServe Español: A Culturally-Appropriate Online Responsible Beverage Service Training for Spanish-Speaking Servers” and is funded by the National Institute of Minority Health and Health Disparities at the National Institutes of Health (R44MD010405. Dr. W. Gill Woodall, a KB Senior Scientist, is the project’s Principal Investigator. Collaborating co-authors on this presentation included Dr. Victoria Sanchez from the University of New Mexico Health Sciences Center, Dr. Areli Chacon Silva and Dr. Frank Perez from the University of Texas at El Paso, and Ms. Jeanny Camacho Reither, KB Senior Project Coordinator.