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Collaborator Spotlight: Utah Investigators on the #4Corners 4Health Project

Collaborator Spotlight: Utah Investigators on the #4Corners 4Health Project

Thirteen scientists from universities and NCI Comprehensive Cancer Centers in Arizona, Colorado, New Mexico, and Utah are collaborating with Dr. David Buller, Klein Buendel’s Director of Research, on the #4Corners4Health study (CA268037). This Collaborator Spotlight features the Investigators from the State of Utah.

The 4Corners study aims to aid rural emerging adults (ages 18-26 years) in making informed decisions that reduce cancer risk factors and prevent cancer later in life and help emerging adults evaluate and resist misinformation and marketing that promote cancer risk behaviors. This will be accomplished using a social media campaign designed with community advisors for diverse young adults living in rural counties in the Four Corners states (AZ, CO, NM, and UT). Social media may reach emerging adults more than interventions through other community channels (for example, clinics, schools, and workplaces) and for lower cost in the geographically dispersed, underserved rural communities in the Mountain West.

Deanna Kepka, PhD, MPH, is a Huntsman Cancer Institute research investigator and a tenured Associate Professor in the College of Nursing. Dr. Kepka is dedicated to improving the quality of primary health care services for cancer prevention and control among underserved populations locally and globally. She has specific expertise in HPV vaccination, HPV-related cancer prevention, and health equity research. She is the founder and director of the Mountain West HPV Vaccination Coalition and the Director of Global and International Health in the College of Nursing.

As a Pre-Doctoral Biobehavioral Cancer Prevention and Control Fellow at the University of Washington and Fred Hutchinson Cancer Research Center, Dr. Kepka developed a rural-focused community-based HPV vaccination intervention that included fotonovela educational pamphlets and a radionovela. These educational tools improved knowledge and sparked interest in the HPV vaccine among rural Latino parents. She also received training in epidemiological and behavioral research methods as a National Cancer Institute Cancer Prevention Post-Doctoral Fellow. As a Fellow, she received the Cancer Prevention Fellowship Merit Award. In the years since, Dr. Kepka’s work has been recognized with 20 awards for excellence at the international, national, local levels.

Echo Warner, Ph.D., MPH, is an Associate Member of the Huntsman Cancer Institute and an Assistant Professor in the College of Nursing. Her research targets improving cancer health outcomes and reducing cancer health disparities among adolescent and young adult cancer patients, survivors, and care partners. Dr. Warner has experience with diverse patient populations and an extensive range of methods and analytical approaches, especially in mixed-methods study designs and data integration. Her research establishes methods to study social media and online health (mis)information to improve cancer information seeking online.

David Wetter, Ph.D., M.S., is the distinguished Jon M. and Karen Huntsman Presidential Professor, Director of the Center for Health Outcomes and Population Equity (HOPE), Senior Director for Cancer Health Equity Science, and Associate Director for Practice Engagement and Translation at the Clinical and Translational Sciences Institute at the University of Utah and Huntsman Cancer Institute. His research focuses on promoting health equity in cancer and chronic disease through translational research. Specific research topics include (a) theoretical models of health risk behaviors; (b) the development and evaluation of theoretically-based interventions; and, (c) translational research to implement and disseminate those interventions in real world settings. His work addresses populations that have been historically marginalized, with a major focus on low socioeconomic status, rural/frontier, and diverse groups. Dr. Wetter has conducted an extensive portfolio of grants funded by the National Institutes of Health over 25 years. He has published nearly 300 peer-reviewed manuscripts. His research program has received awards from the Society of Behavioral Medicine, American Society for Preventive Oncology, Society for Health Psychology, and AstraZeneca/Scientific American.

#4Corners4Health

#4Corners4Health

A collaborative team of highly-experienced cancer prevention and control investigators from the Four Corners Cancer Centers Collaborative (University of Arizona, University of Colorado, University of New Mexico, and University of Utah), Colorado State University, and Klein Buendel is launching a research study that focuses on decreasing cancer risk factors among emerging adults (ages 18-26) living in rural counties in the “Four Corners” states (Arizona, Colorado, New Mexico, and Utah) using a social media campaign. Cancer risks related to infrequent physical activity, unhealthy diet, nicotine product use, alcohol intake, ultraviolet radiation exposure and lack of HPV vaccination are prevalent among emerging adults and contribute to cancer later in life.

The project will test a theory-based, multi-risk factor social media approach to cancer prevention through the use of Facebook and its private group function. Social media can improve information dissemination, credibility, and relevance, be used to detect and respond to emerging trends, and engage users with user-generated content that personalizes information. It offers a superior intervention for emerging adults compared to health care, schools, and workplaces which can be challenging to implement in low-resourced rural communities and will not reach many emerging adults who have low preventive health care utilization, school enrollment, and/or employment.


#4Corners4Health Specific Aims

  • Develop a social media intervention for diverse emerging adults in rural communities via a community-engaged process that combines expert advice, user-generated content, and online instruction about behavioral cancer risks, cancer misinformation, counter marketing, digital and media literacy, and family communication.
  • Evaluate the effect of a theory-based social media intervention on moderate to vigorous physical activity (MVPA), health eating patterns, nicotine product use, alcohol intake, sunburn prevalence, and HPV vaccination with the diverse (ethnically/ socioeconomically) population of emerging adults aged 18-26 in rural counties in the Four Corner states recruited from Qualtrics’ survey panel and enrolled in a pragmatic randomized trial using a stepped-wedge design in which individual emerging adults will be randomized to one of four cohorts and receive social media feed for varying durations in separate Facebook private groups.
  • Test if improvements in merging adults cancer risk knowledge and beliefs, digital and media literacy skills, accurate cancer prevention information, and family communication mediate impact of the social media campaign.
  • Explore whether the impact of the social media campaign differs according to a) level of emerging adults engagement with campaign, b) cancer risk factors, and c) biological sex of the participants.

The investigators hypothesize that (1) emerging adults will increase MVPA and healthy eating pattern, reduce nicotine product and alcohol use, and sunburns, and increase HPV vaccine uptake from pre to post when receiving social media campaign, and (2) positive impact of the social media campaign on cancer risk factors among emerging adults will be mediated by improved cancer risk knowledge and beliefs (self-response efficacy; norms; social support; vaccine antecedents), digital and media literacy skills, misinformation, and family communication.

This research will be led by Dr. David Buller from Klein Buendel and Dr. Andrew Sussman from the University of New Mexico (Multiple Principal Investigators). It is being funded by a 5-year R01 grant from the National Cancer Institute (CA268037). Key collaborators include Dr. Kimberly Henry from Colorado State University; Dr. Cindy Blair from the University of New Mexico; Dr. Judith Gordon, Dr. Cynthia Thomson, and Dr. Jennifer Hatcher from the University of Arizona; Dr. Evelinn Borrayo and Dr. Douglas Taren from the University of Colorado; Dr. Deanna Kepka, Dr. Echo Warner, and Dr. David Wetter from the University of Utah; and Dr. Gill Woodall, Dr. Barbara Walkosz, Dr. Kayla Nuss, and Ms. Julia Berteletti from Klein Buendel.